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This game also features an Free Spins bonus with multipliers up to 500x the bet.<br><br>Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which employed different investigators and ํ๋ผ๊ทธ๋งํฑ ๋ฌด๋ฃ์ฒดํ ([https://justpin.date/story.php?title=the-ultimate-cheat-sheet-for-live-casino justpin.Date]) included participants from different geographic areas. This type of heterogeneity, which is essential for a pragmatic trial to be valid and lessen the chance of bias, is also necessary. However excessive heterogeneity could lead to issues with the design of the trial.<br><br>Pragmatic Play is also a major player in the live casino market, providing an array of table games like as Blackjack and Roulette in various variations. The live studios of Pragmatic Play's offices in Romania and Malta offer customers an authentic gambling experience, as well as a broad range of virtual betting options. 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However, they shouldn't be used to substitute for explanation trials.<br><br>The concept of pragmatism is controversial, and there are concerns about whether pragmatic trials should replace or complement them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which confirm the clinical or physiological hypothesis, and pragmatic trials, which inform the practice and policy decisions. They also suggested a framework known as PRECIS for pragmatic trials.2 This tool tried to define the elements of a practical study that includes recruitment, design, delivery of the intervention and follow-up.<br><br>There is an encouraging increase in the number pragmatic trials published. A recent Medline query that used the words pragmatic and naturalistic, limited to randomised controlled trials (RCTs), returned 34 articles. These are highlighted in red on Figure 2. This is a sign that the health sciences community is becoming increasingly sensitized to the issue of pragmatism. It is important to keep in mind, however, that the majority of these studies were conducted in primary care settings.
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