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Studies designed to provide insight into clinical practice in the real world are referred to as pragmatic trials. They are usually characterized by a focus on the practical aspects of research design, like the recruitment and consent process as well as adherence to the use of commonly available equipment.
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A pragmatic study that involves different investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This type of heterogeneity is necessary for pragmatic trials to be able to prove their validity, and it also helps reduce bias in the results. However, too much heterogeneity can result in problems with the design of the trial.
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Legality
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Pragmatic trials seek to replicate real-life situations and attain maximum external validity. They are typically requested by practitioners and policymakers to inform their decisions. They can be used to determine the cause-effect relationship of an intervention with its outcomes. However, they should not, 프라그마틱 데모 be used to replace explanatory studies.
The idea of pragmatism is controversial and there are concerns about whether pragmatic trials should be used to replace explanation tests or if they should serve as an alternative to them. Schwartz and Lellouch1 suggested a distinction between explanatory studies, which prove a physiological hypothesis or clinical hypothesis, and pragmatic trials, that inform policy and practice decision-making. They also proposed a framework called PRECIS for pragmatic trials.2 This tool attempted to define the characteristics of a pragmatic research study, including recruitment, design, delivery of the intervention, and follow-up.
The number of pragmatic trials is increasing. A recent Medline search using the keywords naturalistic and pragmatic, limited to controlled trials that are randomized (RCTs), yielded 34 articles, as shown in red in Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatic thinking. However, it is important to note that the majority of these studies were conducted in primary care settings.